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What Vitamins Help With Migraines

What Other Supplements Does Cove Offer

Vitamin D could help with migraines, experts say

Riboflavin isn’t the only supplement with strong clinical evidence showing it can help block migraines before they start: Magnesium and CoQ10 can also help cut down your headache days. To get the most impact out of all three, try Beam, a first-of-its-kind migraine supplement from Cove that combines clinically-effective doses of all of these nutrients in one daily powder packet. You can also order riboflavin, magnesium, or CoQ10 supplements individually through Cove. Get started here.

Are you feeling like a riboflavin expert yet? That may have been a lot to take in, but to sum it all up, riboflavin is a relatively safe, research-backed treatment to reduce your migraine frequency. Plus, itâs safe to use with prescription preventive medications.

The information provided in this article is not a substitute for professional medical advice, diagnosis, or treatment. You should not rely upon the content provided in this article for specific medical advice. If you have any questions or concerns, please talk to your doctor.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

What Vitamins Are Good For Menstrual Migraines

In a nutshell, the answer to this question is all of them! If you are low in any of the vitamins, then it could be influencing your ability to develop migraines. Vitamins and minerals work together in the body and its rare that you will be low in only one of them. Vitamin and mineral deficiencies come in packs.

For example, if youre low in vitamin C, you are also most likely to be low in vitamin E and vitamin A. These three antioxidants work together in the body. Vitamin C protects vitamin E and A so they wont be used up in the body. Vitamin E and A do the same. Thus, if you raise one of them without raising the rest of them, you risk causing a deficiency of the others you dont take.

This is why its often best to either take a multivitamin multimineral to get all the dosages right. By just taking vitamin supplements one by one, its guesswork. Ultimately, the best way to know what you should be taking is to see a clinical nutritionist who can balance these for you via what is found in lab tests.

Previous Research Disputes Vitamin Ties

Most importantly, we need to remember that this is not the first time researchers have looked at vitamin levels as a possible cause or contributor to migraines. Theres been enough research done on vitamin D for people to conclude that there is;no link between the nutrient and migraines. There is little support for other nutrients cited in this stud, as well.

Overall, this leads us to conclude that vitamin deficiency cant be a major contributor to migraines for many people.

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Does Riboflavin Help Prevent Migraine Attacks

If youâre probably getting enough riboflavin from your diet, shouldnât you already be getting all of its migraine prevention benefits? Not exactly.

In studies of riboflavinâs effect on migraine headaches, participants are typically asked to take a lot more riboflavin than youâre likely to get from your dietâ400 mg. At that dose, riboflavin has been shown to reduce the number of migraines people experienced each month, although not enough research has been done to know how or why it works.

The evidence for riboflavinâs effectiveness is far from overwhelmingâthere have only been a few clinical trialsâbut the Canadian Headache Society still recommends it for prevention of migraine because the potential for negative side effects is low.

The Top 6 Supplements For Migraines

Blackmores Reme

Written and verified by Holly Hazen

Are you keen to prevent your attacks using supplements for migraines or something more natural than painkillers? Here are the top six most effective and scientifically proven supplements for migraines according to the American Headache Society.

In descending order of preference:

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Vitamins B6 B9 And B12

The flavoenzyme 5,10-methylenetetrahydrofolate reductase regulates the flow of folate between the production of nucleotides and the supply of methyl groups during methionine synthesis and has major effects on the distribution of intracellular folate . MTHFR also plays a pivotal role in the pathogenesis of migraine and hyperhomocysteinemia. The MTHFR enzyme encoded by MTHFR catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, an ethyl group donor to the intermediary metabolite homocysteine during its metabolism to methionine. Methionine is used in the synthesis of the universal methyl donor S-adenosylmethionine. Upon donation of the methyl group, S-adenosylmethionine is converted to S-adenosylhomocysteine, which is subsequently hydrolyzed to homocysteine and adenosine .

Hyperhomocysteinemia is caused by abnormal methionine biosynthesis due to deficiencies in folate, vitamin B12, and vitamin B6 . Folate is also needed to drive the methionine synthesis pathway, as a lack of dietary folate and/or reduced MTHFR enzymatic activity can result in increased homocysteine levels in blood plasma . This relationship makes homocysteine a key intermediate in one-carbon metabolism and further clarifies the involvement of B vitamins in transferring one-carbon units and their relation to the plasma concentrations of total homocysteine .

The 4 Best Vitamins To Help Headaches

Theres a growing interest in using supplemental vitamins to help headaches among migraine sufferers, and for good reason. Over the years, scientists have found convincing proof that supplementing with vitamin B2, magnesium, Coenzyme Q10, and butterbur yields substantially high results in migraine efficacy, while also sustaining optimum neurological and vascular health. Listed are the four best vitamins to help headaches.

Nearly 15% of all people suffer the effects of migraine disorder. Disproportionately, most migraine sufferers are females. Symptoms of migraine attacks range from excruciating headaches and nausea to debilitating fatigue and visual disorders . A migraine attack can last for hours or days, and often require a days recovery.

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Types Of Headache Pain

There are a number of drug treatments that can help in preventing migraines, as well as lessening the frequency and duration of migraine attacks.

Lifestyle changes can also be influential, such as moderating caffeine consumption, avoiding skipping meals, managing allergies, removing food triggers from the diet and performing regular exercise. In addition to these medications and lifestyle modifications, there are a number of natural supplements that can help .

Here is a visual of the eleven types that we will go over in this article.

Migraines Are The Most Common Headaches Around The World

What Lifestyle Changes, Diet And Supplements Will Help Migraine Sufferers?

More than 300 million people worldwide suffer from migraines. Its estimated that nearly 20 million people experience a migraine every day. But, the reason for that migraine could be in your diet. A new preliminarily study by Cincinnati Childrens Hospital Medical Center found that a good amount of children, teens, and young adults who experienced migraines had vitamin D, riboflavin, and coenzyme Q10 deficiencies. Coenzyme Q10 is a natural antioxidant that is similar to a vitamin and can be found in every cell. It helps produce energy to maintain cell growth.

Suzanne Hagler, MD was the lead author on the study. She presented the finding at the Annual Scientific Meeting of the American Headache Society in June 2016. Hagler and her colleagues studied blood samples of 7,420 patients to check for nutrients and vitamins that have been linked to migraines in the past including, vitamin D, riboflavin, coenzyme Q10 and folate.

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Butterbur 50 Mg Two Times Per Day

This herbal supplement may have a role in preventing the inflammatory physical reactions associated with migraine.

Side effects: Mild gastrointestinal symptoms, predominantly burping.

This information is provided purely for informational purposes. This information is not intended to be, and should not be construed as a substitute for, medical or healthcare advice, diagnosis or treatment. Any reader or person with a medical concern should consult with an appropriately-licensed physician or other healthcare provider.

What Are The Symptoms Of A Migraine

Migraines can ache on one or both sides of the head and the pain will usually throb or pulsate. During these episodes, patients may also experience an increased sensitivity to sound and light including vision impairment as well as smell and touch. Migraines can also cause nausea and vomiting. Other unpleasant symptoms include stiff neck, irritability , constipation, yawning, and thirst.

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Best Supplements For Migraine Relief

The content and opinions on Top10Supps are meant to be informative only. They are not medical advice or intended for the diagnosis, prevention, and/or treatment of any health problems. We may receive a commission if you buy something using a link on this page.

A migraine is an intense and prolonged headache, which usually lasts from between 4 and 72 hours . They can be accompanied by other symptoms, such as nausea, vomiting, sensitivity to light, sound, and odor. They can also occur with or without aura . Physical activity can also increase the severity of pain .

Migraines are socially and financially debilitating, for both individuals and society as a whole . They occur more often in women as a result of hormonal influences . The main cause of migraines is unknown but a variety of genetic and environmental factors are involved in their development . We also know that there are different types.

What Is Vitamin D

Migraine Relief Headache Vitamin Supplement Neurologist ...

Vitamin D, also known as the sunshine vitamin, is not really a vitamin. Its a hormone that Ill continue to refer to as a vitamin. Its a critically important hormone like thyroid hormones, insulin, estrogen and testosterone.;

Your body makes Vitamin D when sunlight penetrates your skin.;The amount you make depends on time of year, your skin type and the amount of sun protection you wear.;Its called the sunshine hormone as the warm rays of the sun on your skin make Vitamin D.

When you take supplements or consume Vitamin D in foods, your body converts that to the active, hormone form.;Vitamin D plays an important role in about 3 dozen types of tissues in your body.;This important nutrient and hormone has been found to influence 200 genes. Since studies have identified 40 genes associated with migraine, perhaps there is some overlap that explains the relationship between Vitamin D and migraine.

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How Are These Substances Used

There are two main approaches to treating migraine; treatment of the migraine attack when it happens, and taking regular medications to prevent attacks. Neither of these work 100%, and most people with more severe migraine need to take a combination of the two for best results. All of the substances discussed in this article are used mainly for prevention. Some have been used to treat an acute attack, but this is not discussed further in this factsheet, as there are no research studies for that kind of use.

What Supplements Are Best For Migraine

The three that the American Headache Society reports may prevent migraine attacks are riboflavin, CoQ10, and magnesium.


Riboflavinâalso known as Vitamin B2âis part of the B vitamin family, and it plays a role in helping the body break down foods and regulate energy supply. Itâs found in dairy, grains, some meats, and many green vegetables, so itâs rare for most Americans to be deficient in this vitamin. With that said, it has been shown to play a part in migraine in several studies, including a study in the European Journal of Neurology that showed a significant reduction in migraine frequency for participants taking 400 mg of riboflavin a day for three months.


CoQ10 is an antioxidant chemical that the body produces naturally and can also be found in meat and seafood. Several studies have shown that taking CoQ10 can reduce both migraine frequency and severityâincluding, recently, a 2018 study among 45 women.


Magnesium impacts all kinds of things in the bodyâlike regulating muscle function and keeping blood sugar levels stableâbut itâs also been shown to play a role in migraine. According to a widely cited study, some people experience a drop in magnesium when experiencing a migraine attack. And according to the American Migraine Foundation, some studies have shown that taking magnesium reduces migraine frequency.

The Combination Effect

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The Best Supplements For Migraines

As always, anyone suffering from any form of chronic pain should always refer to their doctor for the best course of action before embarking on any form of treatment. If youve already done so and are ready to feel relief, however, weve rounded up a selection of tried-and-tested supplements for nixing and in some cases, preventing migraines.Keep scrolling for Womans Worlds picks for the best supplements for migrainesto find out what each one does;;and where to find them.

Vitamin B2 And Butterbur

B Vitamins Can Help Relieve Migraine Headaches

Riboflavin or B2 occurs in dairy products, grains and certain plants, and it may have an effect on your cells energy metabolism. As a water-soluble vitamin;its eliminated through the urinary system fairly rapidly, so for treatment and prevention purposes doctors recommend taking two doses of 200 mg each per day. This helps;maintain your levels of B2 for a longer period each day. A dosage of 75 mg a day of butterbur is reputed to have a similar effect to riboflavin, although patients claim it doesnt help as much as the B2.

Negative reactions: Side effects of riboflavin are usually minimal, although high doses can cause your urine to develop an orange color. Patients suffering from hepatitis, cirrhosis of the liver or biliary obstruction may need to take a higher dosage more often to get the same absorption results.

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Vitamins For Migraines And Headaches

When you have a headache caused by vitamins, you may want to see a doctor and discontinue use. However, there are cases where people take vitamins for migraines and headaches.

Magnesium and coenzyme Q10 supplements are often recommended to reduce the frequency and severity of headaches as well as prevent migraines. Some herbal supplements, such as feverfew, have also been known to treat headaches.

Some people have chronic migraines while others may experience headaches as a result of nutrient deficiencies. Headaches and migraines are a reported sign of deficiencies in vitamin B12, vitamin D, magnesium and iron.

Taking vitamins for migraines and discontinuing use of vitamins to prevent headaches may put you at a standstill. To avoid headaches altogether, try to drink plenty of water, eat a balanced diet and exercise regularly. Consult with a medical professional about any vitamins you choose to take.

What Amount Of Vitamin D Should You Take

There is no definitive answer based on the a high degree of individual variation and seasonal exposure to the sun. As a Floridian, I can tell you that there are many people who regularly get adequate daily sun exposure. They eat good sources of Vitamin D yet are still unable to keep it from being low. Getting into the optimal range for helping sleep and migraine would be out of the question for them without significant supplementation.

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Safety Of Supplements For Migraines

Most over-the-counter supplements are generally well-tolerated and safe, but here are some things to keep in mind:

  • Always check with your doctor before starting a new supplement. Some vitamins, minerals, and other supplements can interact with medications you may be taking. They could also aggravate an existing health condition.
  • Women who are pregnant should be especially careful about taking new supplements. Some are not safe for pregnant women.
  • If you have gastrointestinal issues, or youve had GI surgery, you should also talk to your doctor before taking new supplements. You may not be able to absorb them like most people do.

Also keep in mind that when you start taking a new supplement, you may not see results right away. You may need to continue taking it for at least a month before noticing the benefits.

If your new supplement seems to be making your migraines or another health condition worse, stop taking it immediately and talk to your doctor. For example, caffeine may help reduce headaches in some people, but may trigger them in others.

Never assume that all vitamins, minerals, and other supplements are safe, or that theyre of the same quality. For example, taking too much can lead to headaches, nausea, coma, and even death.

Ask your doctor or pharmacist before deciding to try a new supplement brand or dosage.

Not all headaches are migraines. A migraine is a specific subtype of headache. Your migraine symptoms may include any combination of the following:

How Else Can Migraine Be Treated


Some over-the-counter headache medications can help with the pain, such as Tylenol or Excedrin . If your migraine attacks are more severe or frequent, your doctor may prescribe medications or other treatments for you.

For relief without pills, your doctor may suggest trying Botox injections or using a neuromodulation device like the Cefaly Dual.

Resting in a dark, quiet room helps some people. For extra help, a cold compress on the head can have a numbing effect. There are also natural remedies you can try, including supplements like:

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Finding Your Migraine’s Window Of Vulnerability

The FDA is currently reviewing a new migraine drug called Trexima, which combines the migraine drug Imitrex and naproxen sodium contained in Aleve and other over-the-counter medications. The triptan prevents blood vessels from dilating. This dilating leads to migraine pain; the anti-inflammatory drug prevents release of an inflammation-triggering enzyme, according to product developers.

Also in the pipeline: A drug that shows promise as both in preventing migraines and in stopping a migraine once one starts, says George R. Nissan, DO, director of research for the Diamond Headache Clinic in Chicago. The drug works by inhibiting a protein released during inflammation, called calcitonin gene-related peptide . CGRP is found in high levels in migraine patients.

“We’re looking for migraine drugs that don’t have the limitations or side effects of antiseizure or blood-pressure-lowering drugs,” Nissan tells WebMD. “CGRP doesn’t cause constriction of blood vessels, so there would be fewer worries for patients with heart disease, and fewer limitations on its use. However, it may take years until we see it FDA-approved.”

Stephen Silberstein, MD, professor of neurology and director of the Thomas Jefferson University Headache Center in Philadelphia, has led pioneering studies into this “window of vulnerability” during a migraine headache.


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