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How Much Does Botox For Migraines Cost

Prime Therapeutics Finds Members Using Botox To Treat Migraines Didn’t Stay On The Drug Saw Substantially Higher Total Migraine Cost Of Care

Study reveals an opportunity for pricing Botox more closely to its value, assessing the most cost-effective chronic migraine biologic therapy

EAGAN, Minn., March 26, 2019 /PRNewswire/ — A real-world study by pharmacy benefit manager Prime Therapeutics LLC , found while most Botox® use is for chronic migraine prevention at an annual cost of more than $6,300, less than half of new Botox users receive the four recommended treatments during the first year of therapy. Findings also show individuals new to Botox did not see reductions in migraine related medical or pharmacy costs after one year of therapy, but instead had a three-fold increase in total migraine related costs. Botox real-world costs and persistency – staying on the drug as prescribed – prove the need to compare use, cost and persistence to competing drugs in the migraine class when making managed care decisions regarding chronic migraine treatment coverage.

Botulinum toxins are biologic drugs modeled after a neurotoxic protein produced by bacteria and are U.S. Food and Drug Administration approved for a variety of conditions including muscle dystonia, gland secretion and migraine prevention. Botox is the only BT indicated for migraine prevention, and has been the only biologic migraine treatment available for the past eight years. In 2018, Botox’s first biologic competitor for chronic migraine prevention – cGRP products – joined the market following FDA approval.

Can I Combine Botox And Cgrp Antibodies My Insurance Company Refuses To Cover Both And My Physician Told Me I Have To Choose One

CGRP monoclonal antibodies are a new class of treatment for the prevention of migraine. They can be used for Chronic but also Episodic Migraine. Read more here.

Medically, both treatments could be combined. There are reports that this combination might be effective for some people with Chronic Migraine. To read more about the BOTOX®/CGRP MAB combination see here


But Hang On: Migraine Sufferers Who Dont Find Relief From The Typical Drug Classes May Now Benefit From A New Class Of Therapy

Migraines are surprisingly prevalent. They affect 39 million people in the United States.1

Most migraine sufferers experience attacks once or twice a month, but more than 4 million people have chronic daily migraines. That means they have at least 15 migraine days per month; 90 percent of them are unable to work or function normally during those days.1

The good news is that there are several prescription drugs from several different classes that treat acute migraines. Many of those drugs have generics available. Plus, there are new drugs to try and still others in the pipeline. But it can be a real headache for migraine patients to keep trying different drugs, hoping to find one that will give them relief.

Botox Is A Purified Neurotoxin Complex Protein Produced From The Bacterium Clostridium Botulinum

BOTOX is used in adults who have 15 or more migraine headaches per month lasting 4 or more hours per day.

What is Chronic Migraine?

Chronic Migraine is defined as:

  • 15 or more headache days per month over 3 months, with 8 headache days meeting criteria for migraine with or without aura.
  • To meet criteria for migraine, the patient experiences two of the following symptoms:
  • Headache on one side of the head only
  • Headache throbs or pulses
  • Headache is moderate to severe in pain intensity
  • Headache is aggravated by, or causes avoidance of, physical activity and is accompanied by either nausea and/or vomiting or sensitivity to light or sound.
  • Additionally, the migraine sufferer will have treated their headache with migraine medication prior to the expected development of the symptoms listed above.

How is BOTOX administered?

BOTOX is injected by needle into several head and neck muscles that may be causing or contributing to your headaches. The radiologist determines the number of injections and the sites required to treat your specific condition.

How often do I have to get BOTOX injections?

It is recommended that you get your BOTOX injections every 12 weeks. You may continue this therapy, if deemed effective, after discussing with your practitioner.

Can I be treated with BOTOX for chronic migraine if I am receiving BOTOX treatment for another condition?

Should I Pay Injection Fees To The Physician Or The Clinic Where I Receive The Injections

BOTOX in Phoenix & Scottsdale, AZ

This is very variable. Access to care in Canada is supposed to equitable between provinces but it is not the case for migraine care and this is one example.

Alberta and Quebec have fee codes but other provinces don’t. Physicians then have to charge fees directly to patients . Fees may vary between $100 and $200. If you receive your injections from a cosmetic physician, fees might be higher.

My Insurance Company Covers 80% Of Botox Costs For Migraine Do I Have To Pay The Rest

Allergan, the company that makes BOTOX®, offers a co-pay program to help with the cost of treatment. Through this program, you may be eligible to receive up to 20% coverage towards the cost of each BOTOX® treatment.  The program works with physical cards or digital codes depending on the pharmacy you use to fill your BOTOX® prescription, and both of which offer equal access to co-pay support.  Access to the program is managed by health care providers who prescribe BOTOX®.  Ask your health care provider to learn more. 

You’ll Get The Best Value For Your Dollar By Following These 4 Simple Rules:

1.  Pay by the unit, not the area. – This way you only pay for the amount you use. 2.  Follow your injector’s advice. Don’t skimp. – Too little Botox can mean uneven areas or an unnatural look. 3.  Start with the areas that bother you most – BIG improvement in one area will improve your appearance more than a little improvement in 3 areas. 4.  There is no such thing as bargain Botox – If the price is too good to be true, BEWARE.

Why Theres More To It: Migraines And Temporomandibular Joint Disorder

As you can probably tell by this point, the theme with migraine research is that we need to know more than we currently do. I find that people who suffer from migraines— suffer for a long time. Even with medication, some still hurt. Something doesn’t add up in those circumstances. People shouldn’t be suffering when they are taking numerous medications for migraines.

My advice to you is don’t lose faith and keep searching for a better solution. Maybe its botox for migraines, and maybe its not for your particular case. The point is there will be a treatment that works best for you. Don’t lose hope in researching possible solutions.

In my practice, we treat patients with severe TMJ disorder, some of the most severe in the country to be exact. Do you know what they also usually have when I first meet them? Migraines and headaches. That’s not a coincidence.

Here’s the reason why: The muscles of the jaw and TMJ are connected to the head. If the patient has strain from their jaw, from their neck, or from their posture— there’s a good chance they’ll will be susceptible to headaches.

The point is if you have been trying a particular treatment for migraines and it’s not working, talk with your doctor to test another option. Have your jaw evaluated as a possible source. Review your posture throughout the day. Explore if botox can treat the muscles. And have your neck and spine checked to see if there is an orthopedic or neurologic component.

Botox For Migraines & Why Theres More To Headaches Than You Think


Botox for migraines is now an FDA approved treatment for chronic migraines. Does that give you hope? It should. People who suffer from chronic migraines feel like they are driving without a steering wheel. They feel out of control. Their life can become consumed with anxiety for their next bout with migraine pain. That feeling is not only incredibly frustrating. It’s disappointing.

Here are the hard facts: A 2015 study showed that the prevalence of chronic migraines was nearly 1%. Migraine sufferers were more commonly female, in mid-life, and in households with the lowest annual income.

In this article, we’ll discuss how does botox for migraines work, what to expect, how much botox for migraines costs, and why there’s often more to treating migraines or headaches than just botox or any medication for that matter. Let’s talk about migraines, possible solutions, and getting you the relief you deserve.

Everything You Need To Know About Botox Injections For Migraine

Want to find out if Botox injections are the right migraine prevention treatment? Like other chronic pain management procedures, it’s important to consult with a physician first to see if you’re a qualified candidate for the treatment. Here’s everything to know about Botox injection first before utilizing the treatment:

Primes Study On Botox For Migraines Found High Costs And Waste

Most of the time, patients who try Botox have not responded to other conventional migraine therapies. Most of those are generic drugs, taken by mouth. Botox is a biologic therapy. It’s more expensive and requires a health care professional to administer.

The study identified more than 59,000 claims for Botox® from October 2017 to September 2018 among 15 million commercially insured members. Botox for migraines accounted for 65 percent of the category spend. We wanted to look specifically at use of Botox for migraine. A total of 2,473 members met study requirements for continuous enrollment and were identified as new to Botox therapy. For these members, the study showed:

  • Annual cost of Botox for chronic migraine use was more than $6,300 when used according to manufacturer label.
  • Drug waste and provider administration accounted for 34 percent of costs.
  • Less than half of new Botox users received the four recommended treatments during the first year of therapy.
  • Use of Botox did not decrease migraine-related medical or pharmacy costs; rather it was associated with a three-fold increase in total migraine-related costs.

Does Botox For Migraine Help Patients With Vestibular Migraine

The efficacy of Botox for dizziness and vertigo has not been evaluated. Many vestibular migraine patients suffer from symptoms of dizziness and vertigo, some do not experience head pain.

According to a 2017 case report from Korea, a vestibular migraine patient was successfully treated with Botox. She was 58 year old with chronic migraine and recurrent dizziness for 10 years. Medication had not provided satisfactory pain relief and dizziness control. Her intractable head pain and dizziness disappeared 1 day after Botox injections. This case suggested that Botox is effective for dizziness or vertigo in vestibular migraine patients, in addition to being effective for head pain. Further studies are needed to confirm the efficacy of Botox for dizziness and vertigo in migraine patients.

Dr. Alexander Mauskop noted in his 2017 Headache blog that when vestibular migraine patients have frequent headaches he offers them Botox injections, which are not appropriate if headaches are infrequent.

What Can I Expect When I Receive Botox Injections For Migraine


Botox injections to prevent headaches in adults with chronic migraine are generally safe, but they may cause some mild side effects. To learn more, see the “Botox side effects” section above. You can also refer to the “Receiving Botox injections” section above and talk with your doctor.

Botox is approved by the Food and Drug Administration to prevent headaches in adults with chronic migraine.

How Often Do I See My Doctor For Botox Injections For Migraine

You will usually start with 2 treatments spaced 12 weeks apart. Once you and your doctor see how you respond to Botox for migraine, you will then continue treatments every 12 weeks if it is working well for you.

The recommended retreatment schedule of Botox for migraine prevention is every 12 weeks. This means you will only need to receive injections 4 times per year or as directed by your healthcare provider.

Botox For Migraines And Headaches: Costs And Treatment Review

    Headaches are one of the most common nervous system disorders and a major cause of disability worldwide, affecting 47% of adult population in the United States alone. According to the International Headache Society, a headache is classified as a primary headache disorder if the headache itself is the illness and there are no other causes diagnosed. The most common primary headache disorder in clinical practice is migraine. Up to 15% of the world’s population is afflicted with the debilitating disorder. The World Health Organization ranks chronic migraine to be as disabling as dementia, psychosis, and quadriplegia—severely impacting the quality of life. It causes disruption of household and social activities, and functional impairment.

    Deposits And Charges For Cancelling/postponing Appointments

    We take a £50 deposit when making appointments. To cancel an appointment we need 3 full clinic working days. 

    We understand that sometimes it is necessary to postpone an appointment, and we need 2 clinic working days notice to transfer the full deposit to another appointment on the first occasion – discretionary on repeat occasions. However if you contact us by midday the clinic working day before the appointment then the charge can be reduced to £25 and the other £25 can be offset against the £50 deposit for your new appointment. 

    However, we will do our best to offer a replacement appointment on the same day, and if this is possible then there will be no charge for postponing the appointment to later in the day

    If you don’t arrive for your appointment, or cancel/postpone on the day, we will have to make a charge of £50 to contribute towards costs. 

    What Are The Side Effects Of Botox Injections For Migraines

    As with any type of medication, there is always the risk of side-effects when trying a new drug for the first time. It’s no different for Botox. Depending on the dosage you receive and where the application site is, some people may experience headaches afterwards. This is because Botox relaxes your jaw muscles, which allows other muscles to compensate. Fortunately, multi-year studies continue to show that Botox is safe and considerably well-tolerated by most patients. 

    After The Treatment What Comes Next How Long Does It Last

    Some doctors and dermatologists recommend lying down and resting after a treatment, but Ravitz says she doesn’t think there’s any need for downtime unless a patient experiences pain. It can take about two weeks to work, though some patients start to feel relief from chronic migraines sooner than that. Ravitz tells me, “If it’s going to work for a patient, one round of the treatment typically lasts for around three months.” Though everybody metabolizes it at a different rate, getting it done every three months or so has been found to be effective.

    Primes Research Provides The Evidence For Recommendations

    Based on available evidence, we expect similar safety and efficacy in treating chronic migraines from both cGRPs and Botox, although Botox has been on the market longer than cGRPs. Currently, cGRPs appear to be a lower net cost, price to value option for chronic migraine treatment.

    At Prime’s quarterly Medical Business Committee meetings,  we discuss these findings with pharmacy and medical directors from our Blue Plan clients. Together, we work towards ensuring access to the most cost-effective medications to improve health outcomes at the best price to value.

    4. Prime internal data.

    5. Pharmacy Benefit Management Institute. 2019. Trends in Specialty Drug Benefits. Plano, TX. PBMI. Available from www. Reports.

    Drug names are the property of their respective owners.

    How Is Botox For Migraines Different From Cosmetic Botox

    The Botox used for migraines and the Botox used for cosmetic procedures is actually exactly the same. “Basically, young and middle-aged women were getting for cosmetic purposes, and that’s the most common person that has migraines, and that’s how they figured out it was helpful,” Ravitz tells me. Women were getting Botox for aesthetic reasons and happened to notice relief from their migraine symptoms, and doctors began looking into it as a direct treatment. In fact, women are disproportionately affected by migraines — about 85 percent of chronic-migraine sufferers are women, and the condition affects 28 million in just the U.S.

    The only difference between the two procedures is that with Botox for migraines, they may do a few more shots in areas where the pain is experienced. Personally, I usually get between 30 and 40 shots, concentrated mostly on the right side of my head where the pain occurs, at the base of my skull, and on my neck and shoulders, where I tend to hold tension, as doing so can cause a migraine. Botox for migraines can have the same aesthetic effect that cosmetic Botox has, which kills two birds with one stone for people who may desire that effect. “We do it along wrinkle lines and keep it symmetrical,” says Ravitz, which explains the erasing of lines and temporary plumping of wrinkles.

    Is Neck Pain After Botox Injection For Migraines Serious

    How Much Botox Exactly Cost?

    When people hear of Botox, the first thing that comes to their minds is the injectable drug that erases fine lines, wrinkles, and other signs of aging. But aside from its cosmetic uses, Botox injections are also utilized for treating different medical conditions like cervical dystonia, upper limb spasticity, myofascial pain, hyperhidrosis, chronic migraine, and more.

    But is it normal to experience neck pain after using Botox injection for migraine? While using botulinum toxin injections for migraine is relatively safe, some patients might still experience common side effects like neck pain. This usually lasts for a few months until the neurotoxin is metabolized by the body.

    How Is Botox Treatment Different From Dysport Or Xeomin

    Botox, Dysport and Xeomin are all formulated with botulinum toxin type A, and are all considered neurotoxins. Both Botox and Dysport use accessory proteins within their formulation, whereas Xeomin is a “pure” form of botulinum toxin, meaning it doesn’t rely on any accessory proteins. When it comes to treatment of chronic migraines, Dysport and Xeomin have not been studied or tested in clinical trials; currently Botox is the only neuromodulator approved for chronic headache treatment.

    Will My Insurance Cover Botox Injections For Migraines

    Since Botox is an approved treatment for chronic migraines, many insurance companies will cover some — or all — of the costs. This includes both Medicare and Medicaid plans. It’s important to keep in mind that insurance companies will usually only cover Botox treatments if you have tried — and failed — two other treatments for your migraines. To verify this, they may ask that you work with your healthcare provider to submit a prior authorization form. 

    Like with any prescription medication, it’s important to work with your healthcare provider and insurance company to see what cost is covered and what you will be expected to pay out of pocket.

    Possible Side Effects Of Botox Injections For Migraine

    Although Botox cosmetic has already been approved by the FDA for treating chronic migraines, it still comes with different common and serious side effects. Patients need to get the injectable from a trusted provider to avoid serious complications.

    Mild and Common Side Effects

    Botox might cause mild side effects for patients too, just like other medications used for preventing headaches. Most of these common side effects are temporary, lasting only for a few days up to weeks. But if the symptoms worsen or last much longer, it’s better to consult a doctor about the situation so that they may alter the medication plan. Some of the most common mild side effects of Botox injections are drooping eyelid, muscle spasm, neck pain, and pain at the injection site.

    Serious and Long-Term Side Effects

    Although they’re rare cases, patients might also have an allergic reaction to the Botox injection. The neurotoxin might cause life-threatening complications that prevent them from breathing and swallowing. Blindness might also occur if the Botox is incorrectly injected around the eye area. Remember to contact a physician right away if the patient develops serious side effects after getting Botox injections for migraines.

    Read more: Using Botox for Migraine: Side Effects of the Treatment

    What Are The Criteria For My Insurance To Cover Botox

    Different insurance companies have different criteria, but these are frequently seen: 

    Different insurance companies have different criteria, but these are frequently seen: 

    • A diagnosis of Chronic Migraine
    • Previous trial and failure or side effects with 1 or more migraine preventive medications

    Different insurance companies have different criteria, but these are frequently seen: 

    • A diagnosis of Chronic Migraine
    • Previous trial and failure or side effects with 1 or more migraine preventive medications

    Some companies will require a proof of effectiveness, like a 30% or 50% response in frequency, improvement in some quality of life scales . 

    How Long Does It Take For Botox To Work For Headaches

    Botox has delayed action. The effects of botox may begin in 72 hours; however, the majority of people will not see the full results for 10-14 days.

    In the case of treating migraines with botox, however, there’s even more to consider.

    Studies indicate that botox works for migraines over a series of treatments. Patients who received three cycles of Botox for migraine showed that their headache symptoms, and more importantly, their quality of life, continued to improve with treatment. Here’s the good news: Approximately 65% of patients with chronic migraines responded successfully to Botox after 3 courses of treatment.

    And I’ll reiterate one more time in a more concise way. In a recent study of chronic migraine suffers treated with botox this is what was found:

    • 81 percent reported less frequent and/or less intense head pain
    • 61 percent reported excellent pain relief
    • 20 percent reported some pain relief.

    How To Predict If Botox For Migraine Is Going To Help

    In some patients, Botox dramatically reduces the frequency of migraine attacks, while it has no effect for others. Approximately 65% of patients with chronic migraine respond to onabotulinumtoxin A after 3 courses of treatment.

    Dr. Rami Burstein conducted a study published in 2006 which searched for a neurological marker that differentiated between migraine patients who respond to Botox treatment and those who do not benefit from it.

    Different types of pain

    Dr. Burstein found that some patients perceive their pain as pressure buildup inside their head while others perceive their pain to be inflicted from the outside in . 

    Among those who did not respond to Botox, 92% described a buildup of pressure inside their head .

    Among those patients who responded to Botox, 74% perceived their head to be crushed, clamped or stubbed by external forces .

    According to Dr. Mauskop in his 2009 New York Headache blog, many more patients suffer from “imploding” headaches or headaches with pain in the eye than with “exploding” headaches.

    Booking Botox: Finding A Plastic Surgeon In Vancouver

    Getting an appointment for a Botox session in Vancouver, BC is easy and hassle-free. It’s important to choose a clinic which provides high quality work. High quality work also matter a lot when you are choosing a service for your body and face.

    While you can get recommendations from your Dermatologist or friends who have gone through such treatments, we recommend choosing the highest quality providers in your city.

    You can book an online appointment through PlasticSpot for a session with the best clinics in your city. The best plastic surgeons and clinics of America and Canada are advertised through our platform, and many clients find us every month through friends, Google, etc.

    You can request for a free consultation with a medical professional by entering your postal code here.

    Our website specializes in cosmetic surgery and provides a wide range of booking services. It gives you suggestions for the best surgeons found in your area. You can then choose which clinic you want to opt for. It deals with several treatments such as breast augmentation, facelifts, eyelid surgery, liposuction, or tummy tuck. It provides a smooth interaction between the client and the clinic.

    To book an appointment online, you can visit the PlasticSpot website and go through a few steps of choosing some basic questions. They have some generic questions such as gender, what kind of service you want, whether it is your first time, and are you ready or still researching the procedure.


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