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How Long For Topamax To Work For Migraines

Do Topamaxs Side Effects Vary Based On Which Strength Or Dosage Of The Drug Im Taking

Topiramate / Topamax – The Migraine Guy

Possibly. In clinical studies, how often certain side effects occurred varied depending on which dose of Topamax was taken.

For example, the following side effects were more likely to happen with higher doses of Topamax :

  • trouble concentrating

For details about side effects in studies, you can see Topamaxs prescribing information. You can also talk with your doctor or pharmacist.

What Are The Side Effects Of Topiramate

In Summary. Commonly reported side effects of topiramate include: anxiety, ataxia , confusion, diarrhea, diplopia, dizziness, drowsiness, dysphasia, fatigue, lack of concentration, memory impairment, nausea, nervousness, paresthesia, psychomotor disturbance, speech disturbance, depression, visual disturbance, weight loss, dysgeusia, mood changes,

Why Do You Have To Drink A Lot Of Water With Topamax

It is important to drink plenty of water while you are taking topiramate because it can cause an increase in your body temperature and reduced sweating, especially during hot weather and exercise. This can put you at risk of getting dehydrated and can cause kidney stones especially if you are not drinking enough water.

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Is Topamax A Controlled Substance

No, its not. Topamax is available only by prescription from your doctor, but its not a controlled substance.

Controlled substances are drugs that have certain effects that give them a high potential for being misused. They also have a high risk of leading to drug dependence. Because of these risks, there are special rules about how controlled substances are prescribed and dispensed. Topamax doesnt have a high risk of misuse or dependence.

Topamax For Migraine Prevention

Topamax for Migraine Prevention: Dosage and More

Migraine is more than a headache. It often lasts longer and is more severe.

There are many symptoms of migraine, including nausea, vomiting, and sensitivity to light and sound. The major symptom is moderate to severe pain that typically occurs on one side of your head.

Some migraine types present with symptoms that affect the senses, including and especially sight, called migraine with aura.

Aura is a term that refers to symptoms preceding a migraine attack. Migraine with and without aura have different diagnostic criteria and treatment approaches.

Certain drugs are available to help prevent migraine attacks. Migraine prevention drugs are different from drugs that treat migraine attacks that have already started.

You take migraine prevention drugs on a scheduled basis. They help reduce the number of migraine attacks that you have and also help make them less severe.

One of these drugs for migraine prevention is called Topamax .

Topamax belongs to a class of drugs called anticonvulsants. A class of drugs is a group of drugs that work in a similar way.

Although anticonvulsants are used to treat epilepsy, many anticonvulsants are also effective for other conditions, including migraine.

The exact way that Topamax works to help prevent migraine attacks isnt known. Its believed that Topamax calms overactive nerve cells in the brain that lead to migraine attacks.

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Is Anyone Taking Topamax For Migraines

Topamax will not treat a migraine, it will only help prevent one from developing. As with other antiepileptics,Topamax may increase the risk of suicidal thoughts or behavior monitor for worsening depression or mood changes. The dosage of Topamax may need reducing in people with kidney or liver disease.

What Does Topiramate Do To The Brain

Topiramate works by reducing the spread of seizure activity in the brain and restoring the normal balance of nerve activity. For epilepsy brain cells normally talk to each other using electrical signals and chemicals. Seizures can happen when the brain cells are not working properly or working faster than normal.

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Topamax For Weight Loss

Topamax isnt approved for weight loss. However, the drug may reduce your appetite, which may lead you to lose weight.

In clinical studies, weight loss occurred in 6% to 17% of people who took Topamax. This depended on the dosage and condition treated. By comparison, weight loss occurred in 1% to 3% of people who took a placebo .

One review of studies looked at the average weight loss in people who took Topamax. It also looked at how long it took them to lose weight when they took the drug. People who took Topamax for at least 4 months lost an average of 11.8 pounds more than those who took a placebo for the same time period.

Topamax isnt usually prescribed solely for weight loss. But your doctor might recommend Topamax for preventing seizures or migraine if you would also benefit from weight loss. For example, if youre at an increased risk for health problems because of excess weight, Topamax might help you. The drug might also be useful if youre taking other seizure or migraine treatments that can cause weight gain.

There isnt a particular dosage or best time of day to take Topamax for weight loss. You should take it as prescribed by your doctor for seizures or migraine.

If youre interested in taking Topamax for weight loss, its important to discuss the possible risks and benefits of this treatment with your doctor.

The Topamax dosage your doctor prescribes will depend on several factors. These include:

Topamax For Migraine Prevention: Dosage And More

Topiramate (Topamax) : Meds Made Easy (MME)

7 rows · To help prevent migraine, many migraine patients also experience TopamaxQualified doctor ONLY, these are most effective when taken shortly after the start of migraine symptoms for migraines that tend to last longer than 24 hours, Side effects can include worsening of migraine-related vomiting and nausea.Valproate and topiramate might help you have less frequent migraines, nausea and more, You are encouraged to report negative side effects of prescription drugs to the FDA.

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How Long Does It Take For Topiramate To Work For Migraines

Its thought that topiramate calms overactive nerve cells in the brain that cause migraines. For epilepsy, it can take 1 to 2 weeks for topiramate to work properly. For migraines, it can take 1 month for migraine attacks to be less frequent. But it can take 2 to 3 months for topiramate to fully work.

Does Topamax Really Work For Migraines

Although you’ll be taking TOPAMAX® every day, it may take some time to work. In clinical studies, TOPAMAX® was proven to help reduce the frequency of migraines. Some patients experienced fewer migraines after 1 month of treatment however, it may take 2 to 3 months to realize the full benefit of TOPAMAX®.

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Topamax And Other Medications

Below are examples of medications that can interact with Topamax. This section doesnt contain all drugs that may interact with Topamax.

Before taking Topamax, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Topamax and birth control

Topamax can make birth control drugs that contain estrogen less effective at preventing pregnancy.

Examples of birth control pills that can be made less effective by Topamax include:

  • levonorgestrel/ethinyl estradiol
  • desogestrel/ethinyl estradiol
  • drospirenone/ethinyl estradiol
  • norgestimate/ethinyl estradiol

Topamax treatment can also make certain birth control medications less effective at preventing pregnancy. These include:

If you use birth control that contains estrogen, your doctor may recommend switching to a different type of birth control medication while you take Topamax.

Topamax and certain other seizure medications

Taking Topamax with phenytoin or carbamazepine can lower the level of Topamax in your blood. This could make Topamax less effective at preventing seizures or migraine headaches.

Topamax and Depakote

  • acetazolamide
  • zonisamide

What Is The Best Painkiller For Migraines

Topiramate Weight Loss ~ Solution For You About Serious ...

Many people who have migraines find that over-the-counter painkillers, such as paracetamol, aspirin and ibuprofen, can help to reduce their symptoms. They tend to be most effective if taken at the first signs of a migraine attack, as this gives them time to absorb into your bloodstream and ease your symptoms.

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Prevention Of Migraine Progression

A pooled analysis of data from the three pivotal trials suggested that preventive therapy with topiramate 100 mg/day may reduce the risk of progression to chronic forms of headache . This analysis shows that topiramate reduces the risk of an increase in headache rate specifically, patients at higher risk of developing CM appeared to benefit most from topiramate therapy. Furthermore, topiramate reduced the use of acute medication, particularly in patients with high frequency of migraine at baseline.

Data from open-label studies and one small placebo-controlled trial suggested topiramate to be useful also in CM.

More recently, two multicenter, randomized, double-blind, placebo controlled trials, one performed in the USA and the other one in Europe, both published in 2007, demonstrated that topiramate is effective and safe also in patients affected by CM, in the presence or absence of medication overuse, and/or of other migraine prophylaxis . An integrated review of these studies was recently published by Silberstein and colleagues describing differences in patient populations and in the classification of CM between the US and European trials. However, the key difference was the absence of limitation in acute medication intake, which allowed the European trial to demonstrate extended benefit of topiramate also to the subgroup of patients complicated by medication overuse.

Side Effects In Children

Topamax is approved for treating certain types of seizures in children ages 2 years and older. Its also approved for preventing migraine headaches in children ages 12 years and older.

Side effects of Topamax in children are similar to those in adults. These side effects are described above and in Side effect details below.

One clinical study looked at children ages 6 years and older who took Topamax alone for epilepsy. The most common side effects were:

  • fever
  • weight loss
  • respiratory infections, such as colds

In other clinical studies, children ages 2 to 15 years took Topamax with other medications for epilepsy. The most common side effects in these studies were:

  • fatigue
  • sleepiness
  • loss of appetite

In clinical studies involving children ages 12 years and older who took Topamax for migraine, the most common side effects were:

  • abdomen pain
  • respiratory infections, such as colds

Children who take Topamax are less likely than adults to have speech problems, slow reactions, and trouble concentrating.

Serious side effect in children

One possibly serious side effect is more common in children than in adults. Children taking Topamax are more likely than adults to have fever and reduced sweating. These problems can lead to hyperthermia , which may need treatment in a hospital.

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Topamax Recommended Dosage And Costs

Topamax is taken orally. Topamax is the brand name for the generic drug topiramate.

The medication is available in immediate and extended release formulations and in both a brand medication and generic medication. Generic drugs usually cost less and are typically preferred by insurance.

Dosage is currently available in the following forms:

Oral capsule: 15 mg and 25 mgOral capsule: 15 mg and 25 mg
Oral tablet: 25 mg, 50 mg, 100 mg, 200 mgOral tablet: 25 mg, 50 mg, 100 mg, 200 mg

To help prevent migraine, up to 100 mg of Topamax be taken daily by people over the age of 12, administered in two doses.

The recommended starting dosage is 25 mg of Topamax taken once each evening.

After 1 week, the dosage may be increased to 25 mg twice daily. After 2 weeks, 25 mg in the morning and 50 mg in the evening is recommended.

After 3 weeks, the recommended dosage is 50 mg in the morning and 50 mg in the evening. Your dose and titration will be guided by clinical response and tolerability.

The following are the average retail costs of a 1-month supply of Topamax. Be aware that these prices change often, differ by location, and dont include discounts that your insurance company may provide.


What Are The Most Common Side Effects Of Topamax For Migraines

Topiramate – My Experience – Cervicogenic Headaches/Migraines

Though Topamax can be successful in reducing the frequency and severity of migraines, that success often comes at a pricemany people struggle to tolerate the common side effects of the drug, which Dr. Friedman says may include:

  • a tingling, pins-and-needles sensation in the extremities or face
  • loss of appetite leading to weight loss
  • sleepiness/drowsiness
  • nausea
  • brain fog

Dr. Park adds that these side effects can be experienced across the range of dosages for topiramate depending on the individual patient.

I have some patients who get to 100 milligrams twice daily and unfortunately some patients who do not tolerate even 25 milligrams daily, he says.

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How Long Does It Take To Work

Topamax starts working within a couple of hours after you start taking it. However, when you start treatment, your dose is increased slowly over a few weeks. Therefore, it may take a few weeks before the medication level builds up enough for you to notice your seizures or migraine easing.

Even if you dont notice an improvement in your condition right away, its important to keep taking Topamax as prescribed.

Using more than the recommended dosage of Topamax can lead to serious side effects. Do not use more Topamax than your doctor recommends.

How Long Does It Take To Flush Topamax Out Of Your System

Topamax has a half-life of about 21 hours. The half-life of a drug is the time it takes for the amount of the drug in your body to fall by half. It takes about five half-lives for a drug to be almost completely removed from your body. So for Topamax, most of the drug will be flushed out of your system within about 5 days after you stop taking it.

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Office Use Of Topiramate

The two most important rules in the use of topiramate are to exercise patience and discuss side effects in advance.

We begin the use of topiramate by confirming the necessity to use it in the first place. In general, at least four or five days a month of difficult to control headaches would be the usual indication. More severe headaches or headaches with complications would also encourage use of the medication.

Dosing of topiramate should begin low, no more than 25mg at night, but some physicians use even less. The label recommends increasing by 25mg a week but we feel that it is preferable to only increase 25mg every two weeks. If side effects intervene, it may be necessary to slow down the titration process or drop the dose back. Except in the case of the worst adverse events, such as an allergic reaction, we encourage our patients to continue the medication even if mild side effects are encountered.

Financial And Insurance Assistance

Approved for prevention of both migraine and epilepsy ...

If you need financial support to pay for Topamax, or if you need help understanding your insurance coverage, help is available.

Janssen Pharmaceuticals, Inc., the manufacturer of Topamax, offers a savings card that may help lower the cost of Topamax. For more information and to find out if youre eligible for support, visit the manufacturers website.

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For Females Using Topamax

Females using Topamax should use an effective method of birth control to help prevent pregnancy. However, Topamax can make birth control drugs that contain estrogen less effective at preventing pregnancy.

Examples of birth control that can be less effective when taken with Topamax include:

  • levonorgestrel/ethinyl estradiol
  • desogestrel/ethinyl estradiol
  • drospirenone/ethinyl estradiol
  • norgestimate/ethinyl estradiol

Topamax treatment can also make certain birth control medications less effective at preventing pregnancy. These include:

If you use birth control that contains estrogen, your doctor may recommend switching to a different type of contraception.

Will Topamax Make Me Feel High

It depends on how you define feeling high. Typically, feeling high describes feelings of pleasure or extreme happiness. Topamax doesnt have this type of effect.

Topamax is more likely to make you feel sleepy, low in energy, or a bit dazed and confused. You may also have trouble with concentration, memory, or speech while taking it. But some people may also describe these very different effects as feeling high.

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Treatment Of Chronic Migraine With Topiramate

Headache is a very dynamic disease. The transition from episodic to chronic migraine is not uncommon. Approximately 3% to 4%,,, of the general population suffer from chronic daily headache that was defined by Silberstein et al as headache lasting at least 4 hour per day with over 15 headache days per month. Chronic migraine , chronic tension type headache and medication overuse headache are the most common forms of chronic daily headache. The most important risk factors for the development of CM are medication overuse and a high baseline attack frequency. The revised ICHD-2 defines CM as headaches occurring 15 days per month, with at least 8 attacks fulfilling criteria for migraine without aura or responding to acute migraine medication . Alternative definitions for CM are being discussed in the literature and final consensus has not yet been reached.

Topiramate 100 mg/day seems to be effective in the treatment of chronic migraine. Lower dosage of 50 mg/day may also be effectivel. General treatment effect appears to be independent from medication overuse, thus it may not be necessary to withdraw patients with CM from medication overuse prior to a treatment attempt with topiramate.


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