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How Long Does It Take Topamax To Work For Migraines

Topamax Weight Loss Dosage

Topiramate / Topamax – The Migraine Guy

Some research suggests that there is an ideal daily dosage of Topamax specifically for weight loss. Those that consistently take between 100 mg and 200 mg of Topamax daily, have reported that weight loss is virtually effortless. Most people taking the drug within this dose range end up losing between 15% and 20% of their baseline bodyweight. Some speculate that dosages above 200 mg may result in more drastic weight loss.

Topamax For Weight Loss

Topamax isnt approved for weight loss. However, the drug may reduce your appetite, which may lead you to lose weight.

In clinical studies, weight loss occurred in 6% to 17% of people who took Topamax. This depended on the dosage and condition treated. By comparison, weight loss occurred in 1% to 3% of people who took a placebo .

One review of studies looked at the average weight loss in people who took Topamax. It also looked at how long it took them to lose weight when they took the drug. People who took Topamax for at least 4 months lost an average of 11.8 pounds more than those who took a placebo for the same time period.

Topamax isnt usually prescribed solely for weight loss. But your doctor might recommend Topamax for preventing seizures or migraine if you would also benefit from weight loss. For example, if youre at an increased risk for health problems because of excess weight, Topamax might help you. The drug might also be useful if youre taking other seizure or migraine treatments that can cause weight gain.

There isnt a particular dosage or best time of day to take Topamax for weight loss. You should take it as prescribed by your doctor for seizures or migraine.

If youre interested in taking Topamax for weight loss, its important to discuss the possible risks and benefits of this treatment with your doctor.

The Topamax dosage your doctor prescribes will depend on several factors. These include:

Reason For Pbs Listing

The Pharmaceutical Benefits Advisory Committee recommended listing on the basis of acceptable cost-effectiveness compared with placebo for migraine prevention in patients unable to take a beta blocker and/or pizotifen.1 The PBAC noted that there was insufficient evidence that topiramate was effective in prior treatment failure and limited the listing to patients with contraindications or poor tolerance to longer-established migraine-prevention drugs.2

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How Topamax Works For Weight Loss

The mechanism behind how Topamax works is relatively misunderstood. It has been tested in clinical trials for weight loss, but was inevitably discontinued as a result of people experiencing a significant number of adverse effects. Although the drug never lasted in clinical trials for weight loss, many doctors are knowledgeable that patients taking Topamax are likely to lose some weight. Below is a list of factors that may influence how Topamax works to promote weight loss.

Note: What leads to weight loss in one person may not be the same as in another. Therefore it is important to understand that certain factors may be more influential in one persons weight loss than another. For example, one person may predominantly experience poorer taste, while another may have a reduced appetite and diarrhea.

% Of Sumatriptan Users Reported An Adverse Event; Most Minor

Does Topamax 25 Mg Cause Weight Loss

2828 adverse events have been reported from 1678 patients. The term events is used, rather than reactions, as it is uncertain whether some common events are due to the disorder being treated or to the medication. The reporting rate for injections is twice that of the tablets and for women it is 1.6 times greater than for men .

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What Special Dietary Instructions Should I Follow

Talk to your doctor about increasing the amount of food you eat if you lose weight while you are taking topiramate.

Talk to your doctor before changing your diet or beginning any type of weight loss program. Do not follow a ketogenic diet or any other high-fat, low-carbohydrate diet, such as the Atkins diet, while you are taking this medication.

What Is The Average Weight Loss On Topamax

One review of studies looked at the average weight loss in people who took Topamax. It also looked at how long it took them to lose weight when they took the drug. People who took Topamax for at least 4 months lost an average of 11.8 pounds more than those who took a placebo for the same time period.

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How To Use Topamax

Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking topiramate and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually twice daily. Swallow the tablets whole since breaking them may leave a bitter taste. To prevent kidney stones from forming, drink plenty of liquids while taking this medication unless your doctor instructs you otherwise.

Dosage is based on your medical condition and response to treatment. For children, the dosage is also based on weight. Your doctor will gradually increase your dose to reduce your risk of side effects. For some conditions, you may start treatment with topiramate once daily at bedtime and slowly increase your dose to twice a day. It may take several weeks or months to reach the best dose for you and to get the full benefit from this medication.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.

Tell your doctor if your condition persists or if it worsens.

What Kind Of Side Effects Can I Expect

Topiramate – My Experience – Cervicogenic Headaches/Migraines

Have you ever experienced cognitive lapses or difficulty remembering your words?

Brain fog can be a symptom of migraine attacks and it is also a side effect of Topamax. In fact, the brain fog has earned Topamax a nickname in the migraine community: Dopamax. Other common side effects are weight loss due to loss of appetite, tiredness, drowsiness, dizziness, tingling of the hands/feet, or a metallic taste in your mouth. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

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Topiramate May Cause Other Side Effects Tell Your Doctor If Any Of These Symptoms Are Severe Or Do Not Go Away:

  • numbness, burning, or tingling in the hands or feet
  • slowed reactions
  • uncontrollable shaking of a part of the body
  • uncontrollable eye movements
  • change in ability to taste food
  • dry mouth
  • back, muscle, leg, or bone pain
  • missed menstrual periods
  • difficulty urinating or pain when urinating
  • fever or other signs of infection

Topiramate may cause osteoporosis in adults and rickets in children. Topiramate may also slow the growth of children and may decrease the final height that children reach. Talk to your doctor about the risks of taking topiramate.

Topiramate may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s MedWatch Adverse Event Reporting program online or by phone .

What Are Some Migraine Risk Factors And Triggers

Some things make you more likely to get migraine headaches . Other things may bring on a migraine .

Common migraine risk factors include the following:

  • Family history: You are much more likely to have migraines if one or both of your parents had migraines.
  • Sex: Women are more likely than men to have migraines.
  • Age: Most people have their first migraine during adolescence, but migraines can start at any age, usually before age 40.

Common migraine triggers include the following:

  • Food and drink: Certain food and drink may cause migraines. Dehydration and dieting or skipping meals may also trigger migraines.
  • Hormone changes: Women may experience migraines related to their menstrual cycles, to menopause, or to using hormonal birth control or hormone replacement therapy.
  • Stress: Stress may trigger migraines. Stress includes feeling overwhelmed at home or work, but your body can also be stressed if you exercise too much or dont get enough sleep.
  • Senses: Loud sounds, bright lights , or strong smells may trigger migraines.
  • Medicines: Certain medicines may trigger migraines. If you think your migraines might be related to your medicine, talk to your doctor. Your doctor may be able to prescribe a different medicine.
  • Illness: Infections, such as the cold or the flu, may trigger migraines, especially in children.

Foods that may trigger migraines:

  • aged, canned, cured, or processed meat
  • aged cheese

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Why Is Topamax Prescribed

Topamax , classified as an anticonvulsant medicine, is an oral medication taken alone or with other medicines to control certain types of seizures due to epilepsy and for the prevention of migraine headaches.

It is approved by the FDA:

  • to treat certain types of seizures in adults and children 2 years and olde
  • for use with other medicines to treat certain types of seizures in adults and children 2 years and older
  • to prevent migraine headaches in adults and adolescents 12 years and older.

Topamax may cause drowsiness, dizziness, blurred vision or impair your thinking and reaction time. Avoid driving or operating machinery until you know how this medicine will affect you.

You can take Topamax with or without food. The tablets are bitter so do not break, crush or split them. Do not drink alcohol while taking Topamax as it may worsen side effects like drowsiness or dizziness. Drink plenty of fluids during the day to help prevent kidney stones.

Can Topamax Be Crushed Split Or Chewed

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It depends on which form of Topamax you take.

You should not crush, split, or chew Topamax tablets, as they have a very bitter taste. These tablets should be swallowed whole.

If you take Topamax sprinkle capsules, you should swallow them whole. But if you have trouble swallowing them, you can split them open. Then youll sprinkle the contents of the capsule onto a spoonful of soft food, and swallow this right away without chewing it.

If you have trouble swallowing Topamax tablets, talk with your doctor about using Topamax sprinkle capsules instead.

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Dosage For Preventing Migraine Headaches

Topamax is recommended for preventing migraine headaches* in adults and in children ages 12 years and older. The usual recommended dosage is 50 mg taken once in the morning and once in the evening.

Your doctor will gradually increase your dosage to this level over the first 4 weeks of treatment. This allows your body to get used to the medication and helps reduce the frequency and severity of side effects.

The dosage is usually increased as described below, but it may be raised more slowly if needed:

  • Week 1: 25 mg every evening
  • Week 2: 25 mg every morning and 25 mg every evening
  • Week 3: 25 mg every morning and 50 mg every evening
  • Week 4: 50 mg every morning and 50 mg every evening

* For details on the uses of Topamax, see the Topamax uses section above.

Does Topamax Cause Hair Loss

The hair loss was reversible upon discontinuation of topiramate, but recurred after reintroduction of the drug. Hair loss should be considered an adverse effect in topiramate adjunctive therapy. It may have significant cosmetic impact and psychosocial relevance, especially in children and young adults.

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How Little Is Enough To Make An Impact The Next Day

Like so many other answers to science questions, it depends. Body weight and gender are very important factors. While five to eight drinks for the average man, and three to five drinks for the average woman, are enough to cause some degree of hangover, specific effects will vary greatly between individuals. Certain ethnic groups have a genetically reduced ability to break down acetaldehyde, the main byproduct of alcohol, as it is first processed in the liver. This results in more reddening of the skin and hangovers at lower amounts of alcohol.

People prone to migraines tend to have more problems with hangovers. People who drink alcohol regularly, or those who are taking certain specific medications that affect liver enzymes, may metabolize alcohol more quickly, having fewer problems with intoxication and hangover as a result. Conversely, there are many medications that interfere with the breakdown of alcohol and acetaldehyde, worsening the consequences of drinking. A thin, Japanese teetotaling woman taking prescription painkillers will clearly have more problems with a few drinks than a 250 pound linebacker who regularly drinks four beers a night.

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Topamax And Other Medications

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Below are examples of medications that can interact with Topamax. This section doesnt contain all drugs that may interact with Topamax.

Before taking Topamax, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Topamax and birth control

Topamax can make birth control drugs that contain estrogen less effective at preventing pregnancy.

Examples of birth control pills that can be made less effective by Topamax include:

  • levonorgestrel/ethinyl estradiol
  • desogestrel/ethinyl estradiol
  • drospirenone/ethinyl estradiol
  • norgestimate/ethinyl estradiol

Topamax treatment can also make certain birth control medications less effective at preventing pregnancy. These include:

If you use birth control that contains estrogen, your doctor may recommend switching to a different type of birth control medication while you take Topamax.

Topamax and certain other seizure medications

Taking Topamax with phenytoin or carbamazepine can lower the level of Topamax in your blood. This could make Topamax less effective at preventing seizures or migraine headaches.

Topamax and Depakote

  • acetazolamide
  • zonisamide

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What Is Topiramate And How Does It Work

Topiramate is an oral drug that is used to prevent the seizures of epilepsy. It is an anti-epileptic or anti-seizure drug. It is used primarily among patients who are not controlled by other anti-epileptic drugs. About 1 in 4 Americans diagnosed with epilepsy has seizures that resist treatment with other anti-epileptic drugs. Topiramate also preventsmigraineheadaches.

Seizures are due to the abnormal activity of nerves in the brain, and the abnormal activity spreads to smaller or larger portions of the brain. Although topiramate’s exact mechanism of action is unknown, scientific studies suggest that it may alter neurotransmitters within the brain. Neurotransmitters are chemicals that nerves manufacture and use to communicate with other nearby nerves. By altering the production or action of the neurotransmitters, topiramate may suppress the abnormal activity of the nerves in the brain that cause the seizures or may prevent the abnormal activity from spreading to other nerves. Other studies suggest that topiramate may suppress the nerves directly and make them less likely to fire. The FDA approved topiramate as a tablet in 1997. The sprinkle capsules were approved in October 1998.

What brand names are available for topiramate?

Topamax, Qudexy XR, Topamax Sprinkle, Topiragen, Trokendi XR

Is topiramate available as a generic drug?


Do I need a prescription for topiramate?

Is Topamax A Controlled Substance

No, its not. Topamax is available only by prescription from your doctor, but its not a controlled substance.

Controlled substances are drugs that have certain effects that give them a high potential for being misused. They also have a high risk of leading to drug dependence. Because of these risks, there are special rules about how controlled substances are prescribed and dispensed. Topamax doesnt have a high risk of misuse or dependence.

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What Is The Dosage For Topiramate

  • Most commonly, topiramate immediate release tablets and sprinkles are started in low doses, 25 or 50 mg per day, and then increased slowly by 25 to 50 mg per week until an effective daily dose is reached for treatment of seizures. For children 10 years or older and adults the dose may be increased by 100 mg in week 5 and 6 when topiramate is used alone. This slow approach to treatment reduces side effects. The recommended final adult dose is 200-400 mg administered as two divided doses daily.
  • In children, the starting dose is up to 25 mg , taken nightly for the first week. The dose is then increased at 1 or 2 week intervals by 1 to 3 mg/kg/day administered in two divided doses. The target dose is 5 to 9 mg/kg per day in two divided doses.
  • Migraine is treated 25 mg nightly for the first week then increased by 25 mg weekly up to a maximum dose of 100 mg administered in two divided doses.
  • Patients should maintain an adequate fluid intake in order to minimize the risk of kidney stones.
  • The recommended dose for extended release capsules is 200-400 mg once daily.

Will Topamax Make Me Feel High

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It depends on how you define feeling high. Typically, feeling high describes feelings of pleasure or extreme happiness. Topamax doesnt have this type of effect.

Topamax is more likely to make you feel sleepy, low in energy, or a bit dazed and confused. You may also have trouble with concentration, memory, or speech while taking it. But some people may also describe these very different effects as feeling high.

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