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Does Flonase Help With Migraines

Should I See A Specialist For Headaches Caused By Allergies

If over-the-counter medications and lifestyle changes do not fix your allergy headaches, this can lead to additional problems associated with nasal allergies, such as chronic sinus infections. When allergies cause congestion over a significant period of time, this can eventually cause sinus blockages, which can lead to a sinus infection. 

If your allergy headaches and other allergy symptoms persist, it is important to see an allergy or sinus specialist. This specialist can perform an allergy skin test to evaluate your allergies, and even conduct a sinus CAT scan to evaluate your sinuses. An allergist can also recommend stronger, prescription treatments that may be more effective than over-the-counter medications for relieving your symptoms.

If you are struggling to stay on top of your headaches and other allergy symptoms, the experts at Aspire Allergy & Sinus are ready to help. Contact us to make your first appointment and start feeling better faster!

What Is A Sinus Headache

A sinus headache is caused by swelling and pressure in your sinuses. These air-filled cavities usually allow mucus to freely drain and air to easily circulate throughout the nasal passages. When they become inflamed, however, mucus becomes trapped and isn’t able to properly drain. This condition is known as sinusitis, and it can be caused several things, including a cold, flu, or allergies.

As pressure builds up, it causes pain that feels like a headache.

How Do Migraine Nasal Sprays Work

Nasal sprays for can offer more rapid relief than oral medications. In fact, a 2013 research review showed that it’s possible for nasal sprays to begin to ease the symptoms of an acute migraine attack in as quickly as 15 minutes.

Generally speaking, medications that are given intranasally can be absorbed more rapidly and effectively than oral medications. What’s the reason for this?

Your nasal cavity contains a high amount of blood vessels. This provides a more direct route for the drug into your bloodstream.

When a drug is directly absorbed into your bloodstream, it avoids being broken down by your digestive system or by your liver during first-pass metabolism. This means that more of the drug is readily available to counteract your migraine symptoms.

Now let’s explore the general mechanisms behind the drugs that are used in migraine nasal sprays.

What Migraine Nasal Sprays Are Available

There are several migraine nasal sprays that are currently approved by the Food and Drug Administration . These are:

  • Imitrex. Imitrex is a nasal spray of the triptan drug sumatriptan. It was approved by the FDA in 1997 and is indicated for the acute treatment of migraine attacks with or without aura in adults.
  • Tosymra. Tosymra is also a nasal spray of the triptan drug sumatriptan. It was approved by the FDA in 2019 and, like Imitrex, is indicated for the treatment of an acute migraine attack with or without aura in adults.
  • Zomig. Zomig is a nasal spray of the triptan drug zolmitriptan. It got FDA approval in 2003 and is indicated for helping to treat an acute migraine attack that occurs with or without aura in adults.
  • Migranal. Migranal is a nasal spray of the ergotamine dihydroergotamine. It received FDA approval in 1997 and is indicated for acute migraine attack with or without aura in adults.
  • Sprix. Sprix is a nasal spray of the NSAID ketorolac. It received its FDA approval in 1989 and is indicated for the treatment of moderate to severe pain in adults.

Advances in nasal spray technology are also occurring. For example, according to Impel NeuroPharma, a new drug application has been submitted to the FDA for INP104, which uses a new technology to deliver a dihydroergotamine nasal spray.

What Types Of Migraine Medicines Come As Nasal Sprays

Does flonase help nosebleeds ⚕

There are three classes of medications that are available as nasal sprays for treating ongoing migraine.

  • Nasal Triptans
  • Nasal dihydroergotamine or DHE
  • Nasal ketorolac 2

Nasal triptans and ergotamines are specifically approved to treat migraine. The ketorolac is U.S. Food and Drug Administration approved to fight pain, but not specifically for migraine.

Before Taking This Medicine

You should not use Flonase nasal spray if you are allergic to fluticasone.

Fluticasone can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or recently had. Tell your doctor about any illness or infection you have had within the past several weeks.

To make sure Flonase is safe for you, tell your doctor if you have ever had:

  • sores or ulcers inside your nose;

  • injury of or surgery on your nose;

  • a weak immune system; or

  • any type of infection .

If you use Flonase without a prescription and you have any medical conditions, ask a doctor or pharmacist if this medicine is safe for you.

Tell your doctor if you are pregnant or breast-feeding.

Nasal Spray May Trigger Migraine

2 Min Read

NEW YORK – People with hay fever — more accurately termed allergic rhinitis — may find themselves with a migraine after they use a nasal steroid spray to relieve their stuffy noses.

Dr. Jitka Pokladnikova, of Charles University in Prague, and colleagues reviewed the World Health Organization’s global database and other sources and found an unexpected cluster of 38 cases of migraine suspected to be related to the use of intranasal corticosteroids.

The suspected intranasal corticosteroids included six different drugs: fluticasone, beclomethasone, budesonide, mometasone, flunisolide, and triamcinolone. In 24 cases the intranasal corticosteroid was the only drug used, the researchers report in the medical journal Cephalalgia.

Re-exposure to the intranasal corticosteroid led to a relapse of migraine in eight patients. None of the drugs exceeded the maximum daily recommended dose range in any reported case.

In the 16 reports where time to onset was recorded, migraine developed early in the course of intranasal corticosteroid treatment in 12 cases — within the first four days.

A connection between allergic rhinitis and migraine has already been established. The new findings suggest that, “in addition, intranasal corticosteroids might cause or worsen migraine or migraine-like headache,” Pokladnikova and colleagues conclude.

Can I Use Nasal Sprays With Traditional Migraine Medication

One of the benefits of nasal sprays is that they work quickly enough to be a great option for a back-up medication to use when your first-line treatment just isn’t enough. But not all nasal sprays and oral medications can be safely combined.

Regardless of form, different types of triptans can’t be mixed, so don’t use a triptan nasal spray if you’ve already taken an oral triptan. In addition, DHE and triptans also shouldn’t be used together.

On the other hand, and DHE are not only safe to combine, but are also thought to enhance each other’s effect when used together. You can also safely use triptans alongside NSAIDs.

As always, your doctor is the best person to talk to if you have any questions about specific medication combinations.

Anything Else I Should Know Before Trying Nasal Sprays

Talk to your doctor before trying a nasal spray for migraine treatment if you’re or breastfeeding, and if you have high blood pressure, cardiovascular issues, or kidney problems.

Like other recent innovations in migraine treatment, nasal sprays give you a promising new option to consider when you’re building your treatment plan. For people whose migraines tend to get very severe very quickly, nasal sprays could make a great first-line treatment. And even if that doesn’t describe you, it might not hurt to have a spray as a back-up for your preferred treatment.

The information provided in this article is not a substitute for professional medical advice, diagnosis, or treatment. You should not rely upon the content provided in this article for specific medical advice. If you have any questions or concerns, please talk to your doctor.

Part 3 Of 4:using The Correct Administration Technique

  • 1Shake the pump-bottle gently.XResearch source Do this before removing the sprayer’s dust cover to prevent accidental spraying. You do this for the same reason you may shake a juice before drinking it. Liquid mixtures sometimes separate a bit, and shaking ensures an even distribution of ingredients. This is especially important with medication. Remove the sprayer’s dust cover after shaking the bottle.
  • 2Prime the pump if necessary.XResearch source To use it for the first time or after not having used it for a week or more, you must prime the Flonase bottle. Hold the pump applicator vertically between your forefinger and middle finger. The bottom of the bottle should be supported by your thumb. Point the spray nozzle away from your face and body.
  • The very first time you use a new bottle, press down on the pump six times to let off pressure.
  • To re-prime a bottle you’ve used before, press down and release the pump until you see a fine spray.
  • 3Blow your nose.XResearch source Before using the nasal spray, you need to clear your nasal passages. Otherwise, the medication might get caught in the front of the nostril, where it will be less effective. Blow your nose until you have completely cleared your nostrils.
  • Do not blow your nose after using the spray.XTrustworthy SourceMayo ClinicEducational website from one of the world’s leading hospitalsGo to source
  • What Migraine Treatment Options Are Available

    There are two types of migraine medications. These are abortive medications and preventative medications.

    Abortive medications work to ease the symptoms of an acute migraine attack. You typically take them as soon as you feel the symptoms of a migraine attack coming on.

    A 2021 research review estimates that more than 90 percent of people take oral abortive medications for migraine attacks. However, some of these medications are also available in the form of a nasal spray, including:

    • the triptans and zolmitriptan
    • the ergotamine dihydroergotamine

    What Are The Symptoms Of A Sinus Headache

    Sinus headaches often cause the following symptoms:

    • Pressure and pain in your face or head
    • Pain that gets worse when you bend over, move suddenly, or lie down
    • Pain that’s worse in the morning
    • Pain that gets worse when you’re exposed to sudden temperature changes
    • Swelling in your face
    • Pain in your upper teeth

    Nasal Sprays For The Treatment Of Migraine

    Headache From Nasal Spray

    Nasal sprays can provide relief to migraine patients in as soon as 15 minutes, and are especially useful with nausea and vomiting, or in those who seek to avoid an injection. They are sprayed into the nostril with the head upright. Vigorous sniffing or tipping the head backward puts the medicine down the throat, turning a spray into an oral medication and losing advantages of rapid nasal delivery.

    There are several categories of nasal spray treatment. Nasal triptans and dihydroergotamine , contain migraine-specific treatment. Triptans and DHE are highly effective but do cause blood vessel narrowing and should not be used in people with known or suspected vascular disease. A third nasal option is a non-steroidal anti-inflammatory spray, nasal ketorolac, containing medicine targeting migraine inflammation.

    Many patients have an oral acute treatment for slower onset mild-moderate migraines without vomiting, and a nasal formulation for faster wake­up, throw-up, or more severe migraines. With this plan, one must be careful to choose oral treatment compatible with the nasal spray. Different triptan types cannot be safely mixed, and triptans and DHE also cannot be combined.

    How To Care For A Sinus Headache

    This article was co-authored by Laura Marusinec, MD. Dr. Marusinec is a board certified Pediatrician at the Children’s Hospital of Wisconsin, where she is on the Clinical Practice Council. She received her M.D. from the Medical College of Wisconsin School of Medicine in 1995 and completed her residency at the Medical College of Wisconsin in Pediatrics in 1998. She is a member of the American Medical Writers Association and the Society for Pediatric Urgent Care.There are 16 references cited in this article, which can be found at the bottom of the page.wikiHow marks an article as reader-approved once it receives enough positive feedback. In this case, several readers have written to tell us that this article was helpful to them, earning it our reader-approved status. This article has been viewed 526,993 times.

    Persistent Headache More Typical Of Migraine Than Allergies

    Trying to determine what is headache due to migraine versus what is a headache due to allergies is a common issue, says Hamilton. “We know that a lot of people can have a misdiagnosis of sinus headaches or headaches from allergies, when in fact their headaches are from migraine.”

    Hamilton points to a study published in JAMA Internal Medicine that found that 88 percent of people with a history of sinus headaches actually had a migraine-type headache. “A large percentage of people were misdiagnosed,” she says.

    “The fact is, headache is not a very common symptom, in and of itself, of seasonal allergies or allergic rhinitis. It’s much more common to have symptoms such as nasal congestion, like a stuffy nose or runny nose, and eye watering,” says Hamilton.

    If you do have a headache that persists, it might not be just allergies, she says. “That might be an indication that there’s also migraine going on. Typically, headache can be due a sinus infection or viral or bacterial infection, but it’s rare to have a significant headache from just allergy symptoms,” says Hamilton.

    What Are Some Common Nasal Sprays For Migraine

    The following is a partial list of medications that are available as nasal sprays:

    • Onzetra®
    • Stadol® N.S., a narcotic migraine medicine
    • Sprix®
    • Stuffy or runny nose
    • Dizziness

    These are not all the possible side effects of nasal sprays. Patients should check the specific class of nasal spray for an exhaustive list of side effects and talk to their doctor about what to expect with treatment with nasal sprays.

    How Do I Use Nasal Sprays

    Like all acute treatments, nasal sprays work best when you take them as soon as you feel a migraine coming on. While you might be tempted to follow the advice the school nurse gave you when you got a nosebleed, you actually shouldn’t tip your head back. Doing so makes the medication drip down your throat and get absorbed by your stomach, which slows down the absorption process. For the same reason, try not to sniff too much while the spray is in your nose.

    Since each use should administer a pre-measured amount of medication, you don’t need to worry much about dosage. Just be sure not to use the medication more often than you’re directed to.

    Does Flonase Cause Migraine Headaches

    Guest over a year ago


    jolynn40150 over a year ago

    MilaRain over a year ago

    YES! {If you would like to see the numbers and research for this topic, check out

    ***this post is edited by moderator *** *** web addresses not allowed***Please read our Terms of Use

    } I may be a rare case, but every time I use flonase , I suffer from a horrible migraine within an hour of using it and it will last 3-5hours. Years ago, this was not the case, I used it for at least 3 years during spring and fall allergy seasons and had few side effects. But now that I am older , it has become obvious that I can not use such medications anymore. I am stuck with just using Claritin-D and using saline sinus rinse daily during allergy seasons.

    joe over a year ago

    Side Effects Of Nasal Steroids

    It’s important to know that nasal steroids sprays are safe to use for all adults. However, for children, make sure that you use one that’s approved for children age 2 or over.

    Some common short-term and long-term side effects that may occur when using intranasal steroid sprays like FLONASE allergy relief nasal sprays, include:

    •  Burning
    •  Other irritation inside the nose

    Other possible side effects of FLONASE include:

    • Occasional nosebleeds 

    Migraine And Sinus Headache Have Overlapping Symptoms

    Part of the reason for confusion is because oftentimes, migraine-related headaches mimic what people typically think of as sinus headaches, she explains. “You can have pain over the and over the face with both types of headache. With migraine, there can also be symptoms that are similar to allergy symptoms, like a stuffy or runny nose and eye tearing, and that overlap can be why patients are misdiagnosed,” says Hamilton.

    However, there are some key symptoms of migraine that you won’t find in other types of headaches, which can include nausea, vomiting, light sensitivity, and sound sensitivity, according to the American Migraine Foundation.

    Some people with migraine have a visual aura that includes bright spots, lights, or colors prior to the onset of an attack, which wouldn’t happen in a tension-type or sinus headache.

    RELATED: 11 Answers to Your Questions About Light Sensitivity and Eye Pain in Migraine

    So Can Allergies Give You A Headache

    Flonase Nasal Spray For Sinus Infection

    For the record, yes, allergies can cause a headache, says Anastasiya Kleva, MD, a board-certified allergist at ENT and Allergy Associates NY. “They can cause a lot of pain, particularly around the sinuses,” she says.

    How? “You inhale allergens, which cause inflammation in your nose,” explains Lakiea Wright, MD, an allergist/immunologist at Brigham and Women’s Hospital in Boston and the medical director at Thermo Fisher Scientific. “If your nose is congested, the inflammation can also spread to your sinuses. When inflammation accumulates in your sinuses, then you can get a headache.”

    Allergies can also cause your ears to get clogged, and that can lead to a headache, says Purvi Parikh, MD, an allergist and immunologist with the Allergy & Asthma Network.

    Even If You Have Allergies Frequent Headaches May Indicate Migraine

    Hamilton suggests talking with your primary care doctor if you’re having frequent headaches with allergy symptoms. “That might mean that your allergies are actually triggering or contributing,” she says.

    In that situation it might be useful to try migraine medications — both as-needed, or abortive, medications and potentially preventive medications, she adds.

    “If it is a migraine, treating the attack with decongestants, antihistamines, and other allergy medicines typically won’t be as effective as a targeted migraine treatment,” says Strauss.

    “A good rule of thumb is that if you’re not getting complete relief of your headaches from over-the-counter medications, or if the headaches are becoming more frequent or frequent enough that you’re having to take an over-the-counter medication several times a week, you should definitely seek a doctor’s care,” says Hamilton.

    Allergens That Can Cause Migraines

    Migraine Relief Center

      Allergy sufferers have lots to deal with already. Rashes, nausea and breathing trouble are just some of the unpleasant side effects of allergies. Now, it seems you can add causing migraines to the list of possible side effects. A study conducted in 2013 found that allergy sufferers were 33% more likely to suffer from frequent migraines.

      If you’re one of the unfortunate group that suffers from both allergies and migraines, here’s why this is believed to happen, and what you can do for some relief.

      How Do Nasal Sprays Work To Treat Migraines

      First thing’s first: How do nasal sprays work in general?

      Well, when you spray a treatment into your nose, the medication gets absorbed into the blood vessels in your nostril. After that, it’s just like what happens when you take a pill—the medication travels where it needs to go via your bloodstream. So to answer your question, the mechanics of the spray aside, they treat your migraine similar to the way that an oral pill would.

      How It Works

      • Flonase is a brand name for fluticasone nasal spray.
      • Flonase is thought to work by controlling the release of prostaglandins and other substances that promote inflammation. Fluticasone reduces inflammation and relieves itching. It can also help constrict blood vessels.
      • Fluticasone belongs to the group of medicines known as corticosteroids. Specifically, it is a glucocorticoid type of corticosteroid.

      Dealing With Allergy Linked Migraines

      If you are already receiving treatment for migraines, then hopefully the link between your allergies and your headache has been established, and you’re taking steps to manage both conditions. If you’re one of the many who suffer from so called “sinusitis headaches” or you find that certain foods trigger your migraines, then you might not have made the connection yet. Keeping a headache journal and recording when you suffer a migraine and which external factors might be contributing to your symptoms can be a big help.

      As far as limiting the effects of your allergies and hay fever on your head, here’s what you need to know.

      Taking steps to control allergies is likely to reduce the frequency of migraines if they have been a factor in triggering your headaches. Even if you do take all of these steps, however, you may find that you still experience the occasional and debilitating effects of a migraine headache. In that case, specific and specialized treatment for the migraines will be required, and you might need to be prescribed one of the new medications that work to reduce allergy-linked swelling and inflammation. 


      Warning Disclaimer Use For Publication

      WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

      DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

      If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

      What Else Should I Know About Nasal Spray Migraine Medications

      Most of these medications should not be taken if you are pregnant, may become pregnant or if you are nursing. They are also not safe to take if you have heart problems, high blood pressure, circulatory problems, or kidney problems.

      Some of these medicines have been linked to life-threatening conditions when taken in combination with certain protease inhibitors, anti-fungal medications, and certain antibiotics.3

      It’s always important to read the warnings on the drug label, to learn if you should avoid taking the drug as well as what you should discuss with your doctor. You should begin no medication or supplement without first checking with your health care provider and should let them know of any other prescriptions, OTCs, and herbals you are taking to ensure there are no interactions.

      What Is Flonase

      Does fluticasone help with colds . does fluticasone help ...

      Flonase is a nasal spray containing fluticasone propionate. Fluticasone propionate is a that prevents the release of substances in the body that cause inflammation.

      Flonase Nasal Spray is used to treat nasal congestion, sneezing, runny nose, and itchy or watery eyes caused by seasonal or year-round

      Flonase is for use in adults and children who are at least 4 years old and is available without a prescription.

      What Happens If I Overdose

      Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

      An overdose of Flonase is not expected to produce life threatening symptoms. Long term use of steroid medicine can lead to glaucoma, cataracts, thinning skin, easy bruising, changes in body fat , increased or facial hair, menstrual problems, , or loss of interest in sex.

      What Are The Benefits Of Nasal Sprays

      Why would someone choose to spray a medication into their nose when they could just take a pill and get the same effect?

      Nasal sprays work faster

      Nasal sprays usually work more quickly than pills because you don’t have to wait for them to be dissolved and digested by your stomach, a process that slows during a migraine.

      Experts call the time it takes for a medication to kick in “time to peak effect,� so nasal sprays have a shorter time to peak effect than tablets do.

      For example, if you take a tablet as soon as you feel a migraine setting in, you could expect to get some relief from your symptoms in about 30 minutes. But if you use Zomig® nasal spray , you can get that relief in as little as 15 minutes.

      If you’ve experienced a migraine headache, you know exactly what a big difference 15 minutes can make.

      Nasal sprays can be more effective

      The other factor experts consider when choosing what form to recommend is bioavailability, which means how much of the medication enters your blood circulation after you take it.

      Tablets have the lowest bioavailability, and IV treatments unsurprisingly have the highest. Nasal sprays are on the higher end of the spectrum. That means they not only work faster, but are also more efficiently absorbed by your body.

      Nasal sprays don’t interfere with your nausea

      And for people who experience migraine , nasal sprays have an added benefit: You don’t have to swallow them … or worry about vomiting and wasting medication.


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