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Can Benadryl Help With Migraines

Taking Benadryl For Headache And Migraine Can Help In 3 Possible Ways

how to TREAT your HEADACHE: Tylenol & Benadryl

1- The antihistamine action blocks circulating histamine from attaching to cells and causing negative effects like swelling of blood vessels. Also, histamine in the brain promotes wakefulness so blocking this perky chemical messenger may help calm our nervous system.

2- Benadryl provides a welcomed soothing effect for the brain through blocking acetylcholine in addition to histamine. For many of us, sleep or at the very least, rest, is a key part of recovering from an attack. Many people know that they must get at least a short sleep to finally end the attack. Sometimes its Benadryl that comes to the rescue.

3- Benadryl can boost the effectiveness of some medications. Ive never gotten a good explanation of how it happens, but Benadryl has a known effect of boosting the effectiveness of some medications it is taken with. Drug makers know this as its paired with analgesics and cold medications for nighttime sleep. It is often suggested to couple Benadryl with other acute migraine medications to enhance the speed and effectiveness of the primary treatment. Since it can interact with some medications in a good way it can also interact in a bad way so a pharmacist or doctor should be consulted before you use Benadryl for headache and migraine relief.

Can Benadryl Cause Rebound Headaches

People who are habitual of using pain killers for headache and using them for more than 2 to 3 times a week or more than 10 days in a month can develop condition Known as Rebound headaches or Medication Overuse headache.1 Benadryl is not known to cause rebound headache, so far because Benadryl is not a pain killer, it is an anti-cholinergic drug, so it has its own side effects and withdrawal symptoms, it does not produces re bound headaches.2

Rebound headaches or medicine overuse headache is caused when the effect of each dose you take wears off and the pain comes back, causing an urge to take more medicines. This overuse of medicines which you are using to stop the pain is in fact causing more pain and rebound headaches. It can occur when you use OTC medicines, or prescription medicines. Whether you take medicines for headache or any other pain, it can cause rebound headache, but chances for it are more when you are taking medicines for headache or migraine. You can consult a doctor if you feel that you are developing rebound headaches.

Benadryl is an anti-cholinergic drug and excessive use of drugs like these can cause dementia in most of the patients. If we talk to the point, then it is simple that long term use of Benadryl leads to short-term memory loss. The anti-cholinergic drugs affect our central nervous system and make you drowsy. They reduce the brains choline level, which causes the memory impairment in very few days.

What Are The Warnings And Precautions With Migraine Medications

In 2006, the FDA warned about combining triptan drugs with selective serotonin reuptake inhibitors and selective norepinephrine reuptake inhibitors . Taking the drugs together could cause an overload of serotonin in the body, causing what is known as the “serotonin syndrome.â Symptoms of this life-threatening condition include a rapid increase in blood pressure, fast heart rate, and increased body temperature.

SSRIs include:

The use of topiramate can result in decreased sweating and increased body temperature. This may be especially concerning during hot weather. Wearing light clothes and drinking plenty of fluids while using topiramate during warmer months is very important. A physician should be consulted if body temperature rises.

Serious complications of constipation and new-onset or worsening of pre-existing high blood pressure may occur with the calcitonin-gene related peptide antagonist erenumab .

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B Migraine Specific Drugs



Dihydroergotamine is an ergot derivative that is more effective and has fewer side effects than the ergotamine and caffeine combination drugs but is also much more expensive. However, Dihydroergotamine may have a preventative effect too and is much less likely to cause rebound headaches .

Cyproheptadine A Popular Migraine Preventive For Kids

Equate Severe Allergy and Sinus Headache 20 Caplets ...

Cyproheptadine is considered a first-line preventive for some kids who need a migraine preventive. During one of the Migraine World Summits, Dr. Christopher Oakley, a pediatric neurologist specializing in headache disorders spoke about how effective it can be for his young migraine patients. I have heard it described as a more powerful Benadryl with some light Zoloft qualities. The description fits. Like Benadryl, it is a first-generation antihistamine, an anticholinergic and also has a mild serotonin-blocking effects.

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Whats A Rebound Headache

Some headaches rebound because you use medications too much. Then you need to take even more medication, which makes the pain worse. This cycle can happen with:

  • Taking pain relievers more than two days a week.
  • Overusing abortive medications, with headaches returning after the last dose.

Talk to your healthcare provider about stopping medications. If you stop, the pain may improve over the next six to 12 weeks.

Warning Disclaimer Use For Publication

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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What Is Best To Take For A Migraine

Many people who have migraines find that over-the-counter painkillers, such as paracetamol, aspirin and ibuprofen, can help to reduce their symptoms. They tend to be most effective if taken at the first signs of a migraine attack, as this gives them time to absorb into your bloodstream and ease your symptoms.

Benadryl Allergy Sinus Headache Side Effects

Help for cluster headache sufferers

Get emergency medical help if you have any of these signs of an allergic reaction: hives difficult breathing swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking Benadryl Allergy Sinus Headache and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

Stop using the medicine and call your doctor at once if you have:

  • fast, slow, or uneven heart rate

  • confusion, hallucinations

  • tremor, seizure

  • little or no urinating

  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice or

  • dangerously high blood pressure .

Common side effects may include:

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Migraines: Stop Them Before They Start

ARCHIVED CONTENT: As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date each article was posted or last reviewed. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

In her compelling essay, In Bed, novelist Joan Didion wrote, That no one dies of migraine seems, to someone deep into an attack, an ambiguous blessing.

For many people, migraines are debilitating events. As Harvard Health editor Christine Junge wrote in this space last year about her battle with migraine:

On the good days, the pain was just a mild throbbing sensation. Other times, there was a general sense of an ever-tightening pressure. On the days when I couldnt get out of bed, it felt like someone was tightening screws into the sides of my head and pounding a hammer above my left eye. The pain never went away, unless I was asleep.

Most migraine sufferers long to prevent these painful episodes. As I write in this months Harvard Health Letter, about one-third of migraineurs could benefit from taking a preventive pill. But only a minority of them actually take advantage of this option. New treatment guidelines from the American Academy of Neurology and the American Headache Society profile the best preventive medications, and an herbal preparation, for migraine.

Benadryl And H1 Receptors

Many theories into how Benadryl may affect anxiety exist but have yet to be backed up by research.

One of the most popular schools of thought is that Benadryl may improve anxiety symptoms through its affinity for H1 receptors in the body.

The H1 receptor is directly involved with the bodys inflammatory response. Preliminary animal studies suggest that it might also have an impact on anxiety symptoms, but these results have yet to be demonstrated in human studies.

One demonstrated H1 receptor activation in mice resulted in symptoms of anxiety. These symptoms werent observed during the activation of other receptor sites.

Those findings support earlier research in animals from 1999 that showed stimulating or deactivating the H1 receptor could increase or decrease symptoms of anxiety.

But again, this is only seen in animals, and the research is older. Newer studies with actual people are needed, so we dont know whether the process would replicate in humans.

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Is It Possible To Overmedicate

Its tempting and easy to rely too heavily on headache medications. Some people experience daily or almost-daily headaches. For those that get migraines, the headaches may seem to blend together, with no beginning or end. You may feel the need to reach for medications to relieve symptoms or stop headaches in their tracks.

But doing so can actually make headaches worse or more frequent. In particular:

  • Daily or near-daily use of relief medications can interfere with certain parts of the brain. These parts control the flow of pain messages to the nervous system. Over-the-counter medications can pose a risk, including aspirin, acetaminophen, ibuprofen, and drugs with caffeine. So can prescription medications such as triptans, narcotics and barbiturates.
  • Overmedicating with abortive therapies can lower the effectiveness of preventive drugs.

What Is Benadryl Allergy Sinus Headache

Benadryl Severe Allergy And Sinus Headache

Acetaminophen is a pain reliever and a fever reducer.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion .

Benadryl Allergy Sinus Headache is a combination medicine used to treat headache, fever, body aches, stuffy nose, and sinus congestion caused by allergies, the common cold, or the flu.

Benadryl Allergy Sinus Headache may also be used for purposes not listed in this medication guide.

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How Does A Beta Blocker Help Migraines


. Regarding this, how long do beta blockers take to work for migraines?

It can take around three months to determine effectiveness. That can feel like a very long time in which you have little control, which is why we suggest looking into both prescription pain relief medication and research-backed home remedies.

how effective are beta blockers for migraines? A network analysis suggested that betablockers‘ benefit for episodic migraines may be a class effect. For chronic migraine, propranolol was more likely to reduce headaches by at least 50% . The effect began as early as 4 weeks, with migraines reduced by an average of 1.3 headaches per month.

Then, what does propranolol do for migraines?

Propranolol belongs to a group of drugs called beta blockers. It is used in patients with heart problems to control high blood pressure or irregular heart beats. It is also used to treat certain types of vascular birthmarks. It is also used to prevent migraines and headaches.

Do beta blockers cause migraines?

High Blood Pressure and Heart DrugsFor instance, betablockers, which doctors often prescribe to control blood pressure, can also slow down the brain cells linked to migraine. These include: Atenolol

How Should I Take Benadryl Allergy Sinus Headache

Use exactly as directed on the label, or as prescribed by your doctor. Do not use for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.

The chewable tablet must be chewed before you swallow it.

Stop taking the medicine and call your doctor if you still have a fever after 3 days of use, you still have pain after 7 days , if your symptoms get worse, or if you have a skin rash, ongoing headache, or any redness or swelling.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken Benadryl Allergy Sinus Headache within the past few days.

Store at room temperature away from moisture and heat.

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Medications Causing Rebound Headache

Now it is clear from the above discussion that Benadryl is not responsible for causing rebound headaches, it has totally different side effects when taken for long term. It is also important for us to know that which all medications are responsible for causing rebound headaches. The most popular OTC medicines that we use and which are responsible for rebound headache are Excedrin, Tylenol, Excedrin Migraine, NSAIDs like Naproxen and ibuprofen etc. Those medicines which have caffeine as combination have more chances of causing rebound headache. There are some prescription medicines also which are known to cause rebound headache, like Florinal, Fioricet, Vicodin, Tylenol and codeine combination, Percocet etc. The medicines like Maxalt, Imitrex, Triptans, Relpax etc, which are specifically used for migraine can also cause rebound headache or medication overuse headache.4

It is also important to know that over use of Benadryl do not cause rebound headache, neither is it seen during the withdrawal symptoms of Benadryl. The effects related to stopping the use of Benadryl are not as severe as those of alcohol or heroin or but they are worth noting down and cannot be neglected. Till now there is not any such medicine, which is used for the withdrawal symptoms of Benadryl. However, it happens with every medicine that when it is stopped being used, it cause severe withdrawal symptoms. The most common withdrawal symptom of Benadryl includes:

Can Benadryl Be Crushed

New medicine could help prevent migraines

Benadryl tablets can be crushed. If you have trouble swallowing whole tablets, Benadryl liquid solution and chewable tablets are available.

Benadryl is an antihistamine. If you have allergies or have a cold, your body releases a chemical messenger called histamine. This messenger causes symptoms such as inflammation, edema , itchiness, and runny nose.

Benadryl blocks some of the effects of histamine and decreases some of the symptoms caused by it.

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Medications To Relieve Headache Symptoms

How do symptomatic relief medications work?

These medicines help you find relief from the symptoms that may come with headaches, such as pain, nausea and vomiting. Some of these medicines are available over the counter. Others require a prescription.

Try to avoid:

  • Foods, beverages and medications containing caffeine when taking these medications.
  • Medications containing barbiturates or narcotics , if possible.
  • Medications with aspirin, for young children.

Can a child take medications to relieve headache symptoms?

The U.S. Food and Drug Administration has not approved many of these medications for children. Talk to your healthcare provider if your child has headaches or migraines.

What OTC medications can relieve headache symptoms?

These medications provide relief from headache symptoms, without a prescription:

Generic name: Aspirin

  • Brand name: Bayer®, Bufferin®, Ecotrin®.
  • Symptoms relieved: Fever and pain.
  • Precautions and possible side effects: Heartburn, gastrointestinal bleeding, bronchospasm or constriction that causes narrowing of the airways, anaphylaxis and peptic ulcer. Dont give aspirin to children under 14 years old. It can cause a rare but serious disease called Reyes syndrome.

Generic name: Acetaminophen, paracetamol

  • Brand name: Tylenol®.
  • Symptoms relieved: Fever and pain.
  • Precautions and possible side effects: Changes in blood counts and liver function, but side effects are rare if medication is taken as directed.

Generic name: Ibuprofen

When Are Opioids Or Butalbital Useful For Migraines

Your doctor may suggest an opioid if none of the treatments listed above help, or if you have bad side effects.

It is not clear if butalbital should be used at all for treating migraines. If your doctor prescribes butalbital for your migraines, ask why. And ask if there are any other drugs that would work.

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What Else Can I Do

Once you figure out what youâre allergic to, try to avoid it as much as you can.

Manage outside triggers:

  • Stay inside on windy days, when more allergens will be in the air. Mid-morning and early evening are also good times to avoid the great outdoors. Thatâs when pollen counts are highest.
  • Keep your house and car windows closed. Use air conditioning to cool and clean the air.
  • Ask another family member or friend to take care of your yard chores. Mowing, raking, and gardening can stir up pollen and mold.
  • Dry your clothes in a dryer. If theyâre outside on a clothesline, theyâll trap allergens.

Control indoor allergens:

  • Keep your home free of dust. Clean with a wet mop instead of a broom.
  • Use special covers on your box springs, mattress, and pillows to keep out dust mites. Wash your bedding each week in hot water, then dry on high heat.

Avoid pet allergens:

  • Wash your hands after you touch any animal. If it lives in your home, keep it off your bed and out of your bedroom.
  • Keep as few carpets and rugs in your home as you can. Wood floors, tile, and linoleum collect far less dander, the flakes of dead skin that cause most pet allergies. Vacuum any carpet you do have often.

No matter what kind of allergies you have, you can also:

Show Sources

Current Neurology and Neuroscience Reports: âAllergic Rhinitis and Chronic Daily Headaches: Is There a Link?â

Annals of Allergy, Asthma & Immunology: âPrevalence of migraine headaches in patients with allergic rhinitis.â


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